What is the difference between non-invasive DNA and amniocentesis?

What is the difference between non-invasive DNA and amniocentesis?

Having a baby is like leveling up and fighting monsters. Every prenatal checkup is like a challenge. There is more or less nervousness before the checkup, and nowadays there are more and more prenatal checkups, which makes pregnant women more anxious. Many people are worried about what minimally invasive DNA and amniocentesis tests are? What are the differences between the two? Below I will explain in detail the differences between these two pregnancy test methods!

Minimally invasive DNA testing is based on extracting the mother's venous blood (exactly the same as the normal blood test operation) to analyze whether the fetus has three common diseases: 21-trisomy syndrome, 18-trisomy syndrome, and 13-trisomy syndrome. Amniocentesis is a procedure in which a puncture needle or syringe is passed through the pregnant woman's abdominal cavity, through the uterine cavity, into the amniotic cavity, and then the pregnant woman's amniotic fluid or umbilical cord blood is extracted under the guidance of B-ultrasound to obtain the fetus's genetic material for analysis. The two have different accuracy, costs and risks.

1. Different accuracy: The accuracy of minimally invasive DNA is higher than Down syndrome screening and NT, but its accuracy is still slightly lower than amniocentesis. Minimally invasive DNA can help assess whether the probability of fetal chromosomal abnormalities is high or low. Amniocentesis is the gold standard for prenatal examinations at this stage, and it can diagnose whether the fetus has sex chromosome problems.

2. Different costs: The cost of minimally invasive DNA testing is about 2,000 yuan, and amniocentesis is about 1,000 yuan. Although it is not cost-effective, for the health of the fetus, I believe that all pregnant women are willing to try.

3. Different risks: Minimally invasive DNA only requires drawing peripheral blood from the pregnant woman. Compared with amniocentesis, it is much safer and causes less mental stress to the pregnant woman.

Therefore, if you are not old and have missed the Down syndrome screening due to some reasons, or are more concerned about amniocentesis, you can consider doing a minimally invasive DNA test. When minimally invasive DNA testing indicates high risk, or when the baby is conceived through in vitro fertilization, or when B-ultrasound shows that the fetus has malformations, then amniocentesis should be chosen for diagnosis in the most authoritative and accurate way.

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