What causes corpus luteum insufficiency?

Luteal insufficiency is a gynecological disease. Most women with luteal insufficiency often have symptoms of shortened menstrual periods and increasingly regular menstrual cycles. If not treated in time, it will also affect women's reproductive function. Next, let’s understand what causes luteal insufficiency?

1. Defects in uterine and ovarian development and progesterone production: The patient's endocrine disorder causes a lack of follicle-stimulating hormone in the follicular phase, delayed uterine development, and incomplete progesterone development; when the egg is fully formed, the peak secretion of gonadotropin during ovulation is insufficient, which weakens the effect of promoting progesterone production and leads to progesterone dysplasia.

2. Hyperprolactinemia: Inhibits the metabolism of pituitary gonadotropin, and can also directly act on the uterus and ovaries, causing egg hypoplasia or lutein hypoplasia.

3. Incomplete development of the egg itself: The number and function of the egg's granulosa cells are insufficient, resulting in poor luteinization of the granulosa cells and insufficient progesterone metabolism during ovulation.

4. Endometriosis: The patient's abdominal fluid increases significantly, affecting the perfection of the egg and causing luteal insufficiency.

5. In addition: some drugs may cause insufficient ovulation response and excessively high levels of male hormones, which may lead to luteal function defects.

The diagnosis of luteal insufficiency can be based on ovulation temperature, blood progesterone measurement and endometrial puncture biopsy. The ovulation body temperature of this type of patient is biphasic, but the rise and fall are slow, the increase is less than 0.3℃, and the duration is only 9 to 10 days, and sometimes it increases during the follicular phase. On the 8th day of ovulation, the body temperature rises and the blood progesterone level is lower than 10 mg/ml. In the past, endometrial puncture biopsy was usually performed on the 21st to 22nd day of the menstrual period, and the diagnosis standard was that the endometrial phase was more than 2 days lower than normal. Now, it is found that some patients diagnosed with luteal insufficiency are diagnosed with uncleaved ovum syndrome through laparoscopy. Therefore, the diagnosis of this disease should also be combined with B-ultrasound and laparoscopy.

The most common way to treat luteal insufficiency is to supplement the body's progesterone deficiency. Human chorionic gonadotropin can also be used to promote luteal function. In addition, while treating luteal insufficiency, if you can pay attention to the dietary therapy of luteal insufficiency in your life, the patient's condition can be recovered quickly.