Is a transaminase level of over 100 considered high in pregnant women?

Is a transaminase level of over 100 considered high in pregnant women?

After a pregnant woman becomes pregnant, her endocrine system will also change. However, if the transaminase level of a pregnant woman is over 100, this is actually a case of liver damage and requires prompt medical attention. The hormone secretion of pregnant women will change, but there will also be a normal fluctuation value. If the transaminase value is too high, it will also mean that the liver function is abnormal.

After a woman becomes pregnant, the functional burden on the liver increases due to changes in endocrine function and increased blood flow throughout the body. Especially after the second trimester, as the fetus grows, the functional changes in the liver become more significant; in addition, the liver is compressed by the enlarged uterus, and the hepatic circulation is also affected to a certain extent, so the transaminase value at this time may increase slightly. This is a physiological change, which is fundamentally different from organic changes in the liver. It will return to normal after delivery, so there is no need to worry about it.

If the transaminase level is high and exceeds 100 during pregnancy, it should be considered as a possibility of liver damage, which should be treated seriously and actively. You can consider using some drugs such as glycyrrhizin and liver protection tablets for treatment and conduct regular check-ups.

The normal range of transaminase is 0-40U/L. It is an important indicator of liver function. Elevated transaminase indicates liver damage. There are many factors that lead to this, common factors include viral hepatitis, fatty liver, drug-induced liver damage, etc. Drinking is also one of the reasons that lead to increased transaminase. In addition, fatigue, overeating, and lack of rest can also lead to high transaminase levels. It is recommended to test five items of hepatitis B, hepatitis C antibodies and color Doppler ultrasound of the liver and gallbladder to determine the cause and seek treatment as soon as possible.

Causes of high alanine aminotransferase in pregnant women

After a woman becomes pregnant, the functional burden on the liver increases due to changes in endocrine function and increased blood flow throughout the body. Especially after the second trimester, as the fetus grows, the functional changes of the liver become more significant. In addition, the liver is compressed by the enlarged uterus, and the hepatic circulation is also affected to a certain extent. Therefore, alanine aminotransferase levels will be high at this time. This is a normal physiological phenomenon and there is no need to worry too much. It may also be caused by fatigue, eating before the examination, or medication.

It should be emphasized that the high alanine aminotransferase caused by this type of reason is generally just an increase in the amplitude of alanine aminotransferase, but other liver function tests are within the normal range. If the alanine aminotransferase level continues to rise during pregnancy and is very different from the normal value, you should consider whether it is caused by some diseases, such as acute and chronic viral hepatitis, acute fatty liver of pregnancy, intrahepatic cholestasis of pregnancy, pregnancy-induced hypertension or liver damage caused by infection, biliary tract disease, cirrhosis, liver cancer, etc.

1. If you do strenuous exercise, stay up late, do not get enough rest, are overworked, drink alcohol, eat too greasy food, or do not fast for 8 hours before the test, these physiological reasons will cause elevated alanine aminotransferase.

2. Viral hepatitis such as hepatitis B and hepatitis C can cause liver damage and increase alanine aminotransferase when the disease occurs.

3. Liver cirrhosis and liver cancer When liver cirrhosis is active, it can also lead to elevated alanine aminotransferase.

4. Taking drugs that are harmful to the liver can also cause liver damage and increase alanine aminotransferase.

5. Alcoholic liver disease, fatty liver disease and other liver diseases can also cause elevated alanine aminotransferase levels.

6. Acute attacks of cholecystitis and cholelithiasis, a biliary disease, often cause fever, abdominal pain, nausea, vomiting, jaundice, and elevated blood bilirubin and alanine aminotransferase.

7. Alanine aminotransferase may also increase in cases of acute myocardial infarction, myocarditis, and heart failure.

8. Certain other infectious diseases, such as pneumonia, typhoid fever, tuberculosis, infectious mononucleosis, etc., are associated with elevated alanine aminotransferase levels.

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