What to do if the follicle cannot rupture

After a period of development, the follicle gradually matures and then ruptures. Our fertilized egg exists in the tissue of the follicle. Women should perform follicle detection before preparing for pregnancy. If the follicle cannot rupture, it will lead to many situations. However, we can treat it in many ways. So what should we do if the follicle cannot rupture?

Treatment of primary disease: For patients with concurrent diseases such as hyperprolactinemia, PCOS, endometriosis, chronic pelvic inflammatory disease, etc., after a clear diagnosis, medication or surgery will be given to treat the primary disease.

Drug-induced follicle rupture: Individualized ovulation induction plan is formulated and optimized, and after the follicles mature, high-dose HCG or short-acting GnRH-a is injected alone or in combination.

Mechanical treatment: 48 hours after the drug-induced follicle rupture, if the follicle still exists, the follicle can be gently and moderately squeezed by hand under ultrasound guidance. If the follicle still does not rupture, follicle puncture surgery can be performed through the posterior fornix of the vagina under ultrasound guidance to help the egg rupture and be discharged, while also guiding sexual intercourse to try for pregnancy. However, the moderate compression method has limited effect, the puncture method is not cost-effective, and there may be risks such as potential damage and infection, so it is not widely used in clinical practice.

IVF: Patients who still fail to conceive after using the above methods or who have recurrent LUFS are recommended to consider IVF treatment. Through egg retrieval surgery, the eggs are removed and fertilized with sperm in vitro to solve the fertility problem.

Psychological treatment: Relaxation and psychological counseling when necessary can help restore normal ovulation.