What are the symptoms of uterine wall thickening?

The thickness of the uterine wall varies for women at different stages, but it should be maintained within the normal range. It is abnormal for the uterine wall to be too thin or too thick. If the uterine wall becomes obviously thicker, it will cause endocrine disorders in women, and women will age very easily. In severe cases, it will affect women's pregnancy. In more serious cases, it may cause bleeding, which is more harmful.

First, what is endometrial thickening?

Thickening of the endometrium is called endometrial hyperplasia. Endometrial hyperplasia is also called precancerous lesions, which have a certain tendency to become cancerous. Endometrial hyperplasia is a reversible disease that may develop into cancer. The vast majority of endometrial hyperplasia is a reversible lesion or remains a persistent benign state. Only in a few cases may cancer develop after a longer time interval. There are three types of endometrial hyperplasia: simple hyperplasia, complex hyperplasia and atypical hyperplasia.

Second, the symptoms of endometrial thickening

The symptoms of endometrial thickening mainly include irregular vaginal bleeding, irregular menstruation duration, and irregular cycles. Large amounts or prolonged periods of ejaculation can cause anemia in women. The main symptoms are as follows:

1. Women of any age can get sick

Endometrial hyperplasia can occur at any age, during adolescence, the reproductive period, perimenopause, or postmenopause. Elderly patients with severe hyperplasia over the age of 40 should be alert to the possibility of cancer.

2. Vaginal bleeding

The main symptoms of endometrial thickening are irregular vaginal bleeding and menstrual disorders. Infrequent menstruation, amenorrhea, or bleeding that does not stop after a period of amenorrhea. Or it may manifest as irregular menstruation, leading to menstrual cycle disorders, irregular menstrual length, irregular menstrual flow and even heavy bleeding.

There is generally no abdominal pain or other discomfort during bleeding. Large amounts of blood or prolonged bleeding can cause anemia in women, and rapid and heavy bleeding can lead to shock. Therefore, menopausal women must seek medical attention promptly when they experience symptoms of menstrual disorders such as irregular vaginal bleeding. Do not treat it as a normal phenomenon of menopause and not seek treatment or even take random medicines to stop bleeding.

3. Infertility

Thickening of the endometrium can lead to anovulatory dysfunctional uterine bleeding during the reproductive period, so in addition to vaginal bleeding, infertility is also a major symptom for patients.

Third, the cause of endometrial thickening

The main reason for endometrial thickening is excessive estrogen stimulation. Endometrial hyperplasia rarely occurs in women with normal menstrual cycles. When a woman is ovulating, the endometrium will thicken accordingly, which is normal.

1. Causes of abnormal endometrial thickening

If the ovarian hormones are disordered, it can easily lead to abnormal thickening of the endometrium, namely endometrial hyperplasia. The reason for the thickening of the endometrium is that a large amount of estrogen stimulates the endometrium.

Anovulation may occur in adolescent girls, perimenopausal women, disorders in a certain link of the hypothalamus-pituitary-ovarian axis, polycystic ovary syndrome, etc., causing the endometrium to be continuously affected by estrogen for a longer period of time, resulting in anovulation; in obese women, the more adipose tissue there is, the stronger the conversion ability is, and the higher the estrone level in the plasma is, resulting in the continuous influence of estrogen; the gonadotropin function of the pituitary gland is abnormal, and ovarian granulosa cell tumor is also a tumor that continuously secretes estrogen.

Most cases of endometrial hyperplasia occur during menopause or adolescence. The clinical manifestations are irregular and heavy abnormal uterine bleeding. Patients may experience continuous bleeding after a long period of amenorrhea, which may be suspected of miscarriage clinically. It may also manifest as shortened cycles and prolonged menstruation, with bleeding time lasting up to 1 month.

2. Causes of normal endometrial thickening

The uterus has a period of growth every month: it starts around the 5th day of the menstrual cycle and lasts for 7 to 10 days, during which time the estrogen level in the blood gradually increases. The endometrium begins to repair, the endometrium gradually thickens, and blood vessels and uterine glands also grow accordingly, but the endometrium is still very thin at this time; it starts around the 15th day after menstruation and lasts about 14 days. At this time, the follicle in the ovary has ovulated, and a corpus luteum is formed after ovulation. The progesterone secreted causes the already thickened endometrium to continue to thicken, the gland to further enlarge and bend, and to secrete mucus. At this time, the endometrium becomes thick and soft, storing necessary secretions, ready to allow the fertilized egg to implant at any time.