What does high estradiol mean? Ladies, please pay attention.

Estradiol is a sex hormone secreted by the human body. It is not static, and its values ​​are different at different stages of human development. So what does it mean when a physical examination shows high estradiol levels? In fact, there are many reasons that can cause high estradiol levels. Let’s take a look at them together!

1. Normal value of estradiol:

The value of estradiol is not fixed, it changes to a certain extent, and its value is different in different periods. Under normal circumstances, the normal value of women's estradiol is usually 48-521 pmol/L in the preovulation period, but it is 70-1835 pmol/L in the ovulation period, and then it will be 272-793 pmol/L in the postovulation period.

2. The role of estradiol:

1. As one of the sex hormones, estradiol can cause the thinning of the endometrium and less menstrual flow if its value is too low. It can also affect the development of follicles, thus affecting conception. Estradiol is an essential ovarian hormone in the human body. It stimulates the glands in the cervix to secrete a special mucus ("mucus with fertility characteristics"), which is very important for sperm to pass through the cervix and reach the egg.

2. Estradiol also stimulates the growth of the endometrium. Progesterone prepares the endometrium, which has been stimulated to grow by estradiol, for the fertilized egg to implant. When there is no pregnancy, the production of estradiol and progesterone begins to decline about 7 days after ovulation, causing the endometrium to fall off 11 to 16 days after ovulation, resulting in menstrual bleeding.

3. Causes of high estradiol:

High estradiol refers to the estradiol level being higher than normal due to ovarian disease, heart disease, systemic lupus thematosus, etc. Causes of high estradiol levels include:

1. Ovarian diseases: Ovarian granulosa cell tumor, ovarian embryonal tumor, ovarian fat cell tumor, sex hormone-producing tumor, etc., all show ovarian hyperfunction and increased estradiol secretion.

2. Heart disease: myocardial infarction, angina pectoris, coronary artery stenosis.

3. Others: systemic lupus erythematosus, liver cirrhosis, and male obesity.

4. What to do if estradiol level is too high?

High estradiol levels can easily affect ovulation and menstruation, causing infertility. It is best to use hormone drugs for treatment under the guidance of a doctor. If estradiol is high, you can consider using some androgen drugs, which can antagonize estrogen. The most commonly used one is testosterone propionate. You can also consider weak androgen drugs, such as danazol. It is best to take the medicine under the guidance of a doctor.

In addition, people with high estradiol levels should avoid eating foods high in estrogen, but should eat more low-fat, high-fiber foods. Because this type of diet can reduce estrogen levels in the body.

It should be noted that female friends should never take medicine lightly. Because if the estradiol level is high during menstruation, it may be a coincidence and requires symptomatic treatment after a doctor's diagnosis. Regular follow-up examinations should be conducted. If problems are still found during the follow-up examinations, a scraping can be taken for pathological examination.

Warm reminder: If estradiol shows abnormalities for a long time, you need to go to the hospital for examination in time. There are generally two ways to check: blood sample test and urine sample test. You need to fast for 12 hours before a blood test, and be careful not to drink too much water or engage in strenuous exercise before a urine sample test.